Whereas chemicals and waste are integral to almost all sectors of society, they pose grave danger to human health and the environment if not properly managed. Intentional or accidental releases of chemicals and wastes may cause serious damage to soil, water and air with major environmental and health consequences. Whereas the trend in East Africa shows rapid urbanization and increasingly intensified agricultural and industrial production with accompanying heavy use of chemicals and generation of hazardous wastes, majority of the EANECE member countries have largely ineffective policies, legal and institutional frameworks for sound management of chemicals and wastes. This situation leaves the environment and people precariously exposed to the dangers of toxic chemicals and hazardous wastes and materials. EANECE works with member countries and institutions to enhance policy and legal frameworks as well institutional capacities in order to reduce the adverse impacts of exposure to chemicals and waste.